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5-Lipoxygenase antibody [GT124...

Article
5-Lipoxygenase antibody [GT1241]
Product Number
GTX02838-100UL
Supplier
GeneTex
Size
100 ul
Description
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Category
Antibodies
Product Group
Recombinant Antibodies
Application
ICC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Human, Mouse, Rat
Conjugate
Unconjugated
Clone ID
GT1241
Formulation
PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen
A synthesized peptide derived from human ALOX5
Synonyms
5-LO; 5-LOX; 5LPG; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOG5; LOX-5; polyunsaturated fatty acid 5-lipoxygenase
Unigene ID
240
Gene Symbols
ALOX5
Shipping Temperature
BLUE ICE
Supplier URL
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