CHO/Human CD16a (158V) Stable ...
- Article
- CHO/Human CD16a (158V) Stable Cell Line (High Expression) Development Service
- Product Number
- SCCHO-ATP059H-2VIALS
- Supplier
- Acro Biosystems
- Size
- 2 vials
- Description
- CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. The price includes a surcharge of 350 CHF for Dry Ice delivery.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Application
- Binding
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 2 vials
price on request