CHO/Human CD32b Stable Cell Li...
- Article
- CHO/Human CD32b Stable Cell Line (High Expression) Development Service
- Product Number
- SCCHO-ATP060H-2VIALS
- Supplier
- Acro Biosystems
- Size
- 2 vials
- Description
- Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies. The price includes a surcharge of 350 CHF for Dry Ice delivery.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Application
- Binding
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 2 vials
price on request