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Human Amphiregulin protein, Hi...

Article
Human Amphiregulin protein, His and GST tag
Product Number
GTX00421-PRO-10UG
Supplier
GeneTex
Size
10 ug
Description
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Application
Func
Conjugate
Unconjugated
Formulation
Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Synonyms
amphiregulin; amphiregulin B; AR; AREGB; colorectum cell-derived growth factor; CRDGF; schwannoma-derived growth factor; SDGF
Unigene ID
374
Gene Symbols
AREG
Shipping Temperature
BLUE ICE
Supplier URL
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