JMJD2D Strep-tagged (human rec...
- Article
- JMJD2D Strep-tagged (human recombinant)
- Product Number
- 11300-100UG
- Supplier
- Cayman Chemical
- Size
- 100 ug
- Description
- Source: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli • Mr: 42.6 kDa • JMJD2D catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me2/3), leading to transcriptional repression and activation, respectively. JMJD2D is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity. Therefore this protein is purified by Strep-Tactin affinity chromatography.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Kinases & Other Enzymes
- Purity
- ≥70% estimated by SDS-PAGE
- Formulation
- 20 mM HEPES, pH 7.4, and 150 mM sodium chloride
- Synonyms
- [histone H3]-trimethyl-L-lysine(9) demethylase 4D; jmjC domain-containing histone demethylation protein 3D; JMJD2D; jumonji domain containing 2D; jumonji domain-containing protein 2D; lysine (K)-specific demethylase 4D; lysine-specific demethylase 4D
- Unigene ID
- 55693
- Gene Symbols
- KDM4D
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page