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JMJD2D Strep-tagged (human rec...

Article
JMJD2D Strep-tagged (human recombinant)
Product Number
11300-100UG
Supplier
Cayman Chemical
Size
100 ug
Description
Source: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli • Mr: 42.6 kDa • JMJD2D catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me2/3), leading to transcriptional repression and activation, respectively. JMJD2D is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity. Therefore this protein is purified by Strep-Tactin affinity chromatography.
Category
Proteins, Peptides and Small Molecules
Product Group
Kinases & Other Enzymes
Purity
≥70% estimated by SDS-PAGE
Formulation
20 mM HEPES, pH 7.4, and 150 mM sodium chloride
Synonyms
[histone H3]-trimethyl-L-lysine(9) demethylase 4D; jmjC domain-containing histone demethylation protein 3D; JMJD2D; jumonji domain containing 2D; jumonji domain-containing protein 2D; lysine (K)-specific demethylase 4D; lysine-specific demethylase 4D
Unigene ID
55693
Gene Symbols
KDM4D
Shipping Temperature
DRY ICE
Supplier URL
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