A bicyclic monoterpene with diverse biological activities, inhibits proliferation of B16/F10-Nex2 mouse melanoma, as well as human A2058 melanoma, HL-60 leukemia, U87MG glioblastoma, and SK-BR-3 breast cancer cells (IC50s = 71.2, 35.2, 27, 55.4, and 34.7 µg/ml, respectively), increases caspase-3 activity and induces apoptosis and ER stress in B16/F10-Nex2 cells at 70 µg/ml, lowers plasma levels of total cholesterol, LDL cholesterol, and TGs in a Triton WR-1339-induced rat model of hyperlipidemia at 1.5 µg/g, inhibits hepatic steatosis and insulin resistance in a mouse model of high-fat diet-induced obesity at 0.2%, dietary, has larvicidal activity against third instar H. armigera larvae (LC50 = 10.64 µg/ml) and ovicidal activity against H. armigera eggs (EC50 = 35.39 µg/ml)
