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AChE antibody [HL1102]

Article
AChE antibody [HL1102]
Product Number
GTX636298-25UL
Supplier
GeneTex
Size
25 ul
Description
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Recombinant Antibodies
Application
ICC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Cat, Human, Mouse, Rat
Conjugate
Unconjugated
Clone ID
HL1102
Formulation
PBS, no preservative.
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human AChE. The exact sequence is proprietary.
Synonyms
ACEE; acetylcholinesterase; acetylcholinesterase (Yt blood group); apoptosis-related acetylcholinesterase; ARACHE; N-ACHE; YT; Yt blood group
Unigene ID
43
Gene Symbols
ACHE
Shipping Temperature
BLUE ICE
Supplier URL
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